Product Overview
Nilotinib HCL Monohydrate is known as a widely available selective BCR-ABL tyrosine kinase inhibitor.
Primarily used to treat chronic myeloid leukaemia (CML).
As a second-generation tyrosine kinase inhibitor, it is in inhibiting BCR-ABL tyrosine kinase.
Therapeutic Applications
Nilotinib HCl monohydrate is Effective in controlling Philadelphia chromosome-positive chronic myeloid leukemia.
Used in patients with resistance or intolerance to prior therapy, including imatinib.
Investigated in other malignancies involving tyrosine kinase dysregulation.
Specification Parameters
White to off-white powder is the appearance of Nilotinib HCl Monohydrate.
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The molecular formula is C28H22F3N7O.HCl.H2O
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Molecular weight is 583.06 g/mol
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Available in powder form.
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Related substance is ≤ 0.5% (individual impurity).
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The heavy metals specification is ≤ 10 ppm.
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The considered melting point is 230°C – 240°C (approx.).
Packaging & Storage
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Present in sealed HDPE bottles, double-lined drums, or aluminium foil bags.
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The pack sizes available are 1 g, 5 g, 10 g, 25 g, 100 g, and bulk on request.
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Has to be stored or kept in a cool, dry place away from direct sunlight.
Why Choose Us
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Choosing us ensures you receive a high-quality product.
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Our API quality goes beyond pharmacopeial standards.
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We ensure regulatory compliance for global markets.
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Custom packaging and labeling benefit clients’ requirements.
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On-time delivery and responsive logistical support.
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Complete regulatory and technical documentation is available, i.e. (COA, MSDS, DMF support).
