Product Overview
Deferasirox (CAS No. 201530-41-8) is utilized as a drug that removes excess iron from the body.
It is not provided as a finished drug but rather utilized as an active pharmaceutical ingredient to formulate drugs that are beneficial for individuals who undergo multiple transfusions of blood.
These patients often have excess iron in their bodies, which can harm their hearts, livers, or other organs.
Deferasirox works by chelating with the excess iron and helping the body to eliminate it via feces.
It is considered safe and effective when formulated and administered as per regulatory-approved protocols.
It is one of the most important APIs for the manufacture of drugs for thalassemia, sickle cell anemia, and other diseases where iron is accumulated due to repeated transfusions.
Therapeutic Applications
The body’s excess iron is treated with Deferasirox.
This is for people who have a lot of blood transfusions, for instance, thalassemia, or patients with sickle cell disease.
It is also given to persons with non-transfusion-dependent thalassemia.
Too much iron will cause organs to be damaged and serious health complications.
Deferasirox removes iron from the body and prevents these complications.
It is used in the formulation of oral iron chelation therapies, allowing for non-invasive delivery systems.
Doctors use it to treat iron safely over an extended duration of time.
It protects the heart, liver, and other organs.
Specification Parameters
Our Deferasirox API is of better quality and safety levels. Every batch is produced in GMP facilities.
We conduct purity, stability, and quality tests.
We can also provide documents, on demand, to support your formulation processes.
The general properties of our product are as follows:
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Appearance: Off-white powder
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Identification: Satisfies by IR or HPLC
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Assay (on dried basis): No less than 98.0%
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Loss on Drying: Not greater than 1.0%
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Residue on Ignition: Not greater than 0.1%
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Related Substances: Not more than 0.1% for each impurity; total less than 1.0%
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Heavy Metals: Less than 10 ppm
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Solubility: Highly insoluble in water, also soluble in DMSO
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Melting Point: 225°C to 230°C
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Storage: Store below 25°C, protected from moisture and light
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Shelf Life: 36 months if stored as recommended
Packaging & Storage
Deferasirox API is packed with care to make it stable and safe.
All the labels have batch numbers, manufacturing dates, expiry dates, and safety marks.
Keep the medicine somewhere dry and cool.
Store it in a location that is not exposed to sunlight and water.
Although refrigeration is not mandatory, the conditions of storage need to be maintained below 25°C.
We deliver all the handling and safety details so that your personnel can handle the material safely.
We use the best materials to protect it against moisture, heat, and transit loss.
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Packaging Type: HDPE drums or fibre drums with inner polythene liners
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Available Sizes: 1 kg, 5 kg, 10 kg, 25 kg (on demand, custom sizes)
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Sealing: Containers are sealed to avoid tampering
Regulatory & Documentation
Deferasirox API is supported by detailed technical and regulatory documentation.
These documents are of great importance for product registration, regulatory submission, and quality control.
These reports satisfy the health authorities’ needs across various nations and support audits and inspections.
The documents provided tend to be:
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Drug Master File (DMF) or the Active Substance Master File (ASMF)
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Certificate of Analysis (CoA)
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GMP Certificate
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Material Safety Data Sheet (MSDS)
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Stability Reports (accelerated and long-term)
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Method Validation Report
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TSE/BSE Free Certificate
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Non-GMO Declaration
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Residual Solvent Profile
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Elemental Impurity Report
Why Choose Us
Actiza Industry intends to manufacture and deliver quality Deferasirox API.
Our production units are approved and follow WHO-GMP guidelines.
We use modern equipment and strict testing so that the API clears all key tests.
We test each batch in our in-house quality control laboratories as well.
We have a healthy supply chain, so we dispatch promptly to customers in most regions.
Our technical and research staff are ready to meet special needs, such as special procedures or documentation.
We do small and bulk orders and maintain a tight relationship with you throughout.
We work with more than 35 nations globally and establish long-lasting, dignified relationships.
With Actiza, you receive high purity, timely assistance, and reliable service under a single roof.