Product Overview
Cabergoline is a semisynthetic ergot derivative and an established Active Pharmaceutical Ingredient (API).
It is a dopamine agonist drug. The central action of this API is the lowering of the body’s prolactin level.
It does this by directly stimulating dopamine D2 receptors in the pituitary gland.
This feature makes it effective for treating a broad spectrum of endocrine diseases.
Cabergoline is valued for its long half-life and oral ease.
Patients usually need two doses a week, unlike older drugs with a daily dosing regimen.
Such aspects make Cabergoline a preferred choice in its therapeutic categories
Therapeutic Applications
Cabergoline is widely used in endocrinology and neurology.
Its long half-life allows less frequent dosing compared to older drugs such as bromocriptine, making it more convenient for patients
The major uses are:
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Hyperprolactinemia: Overproduction of prolactin causes infertility, irregular menstrual periods, or hypersecretion of milk. Cabergoline lowers prolactin to normal values.
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Pituitary adenomas: In pituitary tumors, it lowers prolactin and may shrink the tumor size.
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Parkinson’s disease: It can improve tremors, stiffness, and movement impairment.
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Hormone disorders: Helpful when low dopamine leads to abnormal hormone secretion.
Specification Parameters
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CAS Number: 81409-90-7
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Molecular Formula: C26H37N5O2
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Molecular Weight: 451.61 g/mol
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Appearance: White to off-white crystalline powder.
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Solubility: Very slightly soluble in water; soluble in chloroform and methanol
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Purity: ≥ 99% by HPLC
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Moisture Content: Not more than 1.0%
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Related Substances: Within pharmacopeia limits
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Standards: Complies with USP and EP specifications
Packaging & Storage
Cabergoline comes in safe and secure packaging to keep it stable.
There are multiple packs of 1 g, 5 g, and 25 g.
It is packaged in HDPE bottles or fiber drums with double liners.
Customized bulk packaging is available as per client requirement.
For stability, the API must be stored in a cool and dry location. The ideal storage is at 2–8°C.
It must be kept away from direct sunlight, heat, and moisture.
The shelf life is 24 months at normal storage conditions.
Regulatory & Documentation
To assist international pharmaceutical partners, complete regulatory documentation is offered.
This documentation ensures smooth registration in both regulated and semi-regulated markets.
This includes:
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Drug Master File (DMF) support
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Certificate of Analysis (CoA) for each batch
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Technical Package (TP) and validation data
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GMP compliance certificates
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Stability studies as per ICH guidelines
Why Choose Us
Choosing Actiza Industry as your supplier ensures quality, compliance, and service reliability.
Actiza Industry is committed to providing APIs that meet the highest global standards.
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High Purity: Produced under GMP with purity ≥ 99%.
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Regulatory Support: Complete DMF and CTD dossiers.
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Reliable Supply: Strong production capacity for steady delivery.
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Global Reach: Exported to regulated and semi-regulated markets.
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Customer Focus: Fast technical and regulatory assistance.
