Product Overview
Bortezomib API is the first proteasome inhibitor of its kind.
Many believe that it’s a big step forward in the fight against blood malignancies.
It specifically goes for the 26S proteasome. This group of enzymes is very important for breaking down proteins that have been tagged with ubiquitin.
Bortezomib API stops proteasomal action. This messes with the turnover of proteins.
This results in cell cycle arrest and death, certainly in malignant plasma cells.
The API is a derivative of boronic acid dipeptide.
It has made things much better for people with multiple myeloma and mantle cell lymphoma (MCL).
This is why it is an important part of today’s cancer chemotherapy programs.
Therapeutic Applications
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Therapeutic class: Antineoplastic / Proteasome Inhibitor
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It is an important solution for people with multiple myeloma who have just been diagnosed or who have had a relapse or are resistant to treatment.
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Approved for usage in Mantle Cell Lymphoma that has come back or hasn’t worked.
Specification Parameters
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The chemical name is [(1R)-3-Methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino].propanamido]butyl] boronic acid
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C19H25BN4O4 is the molecular formula
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Weight of the molecule is 384.24 g/mol
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CAS Number is 179324-69-7
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The colour is white to off-white, and the texture is crystalline powde.
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Purity (by HPLC) is at least 99.0%
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Easily dissolves in DMSO and ethanol, but not very well in water
Packaging & Storage
The following are some of the precautionary rules and secure materials used for the best packaging and storage:
Lyophilised glass vials are often used for therapeutic formulations.
HDPE containers with seals that can’t be broken for bulk API supply
Aluminium foil pouches with desiccant for use in small labs
Keep it at 2–8°C in a controlled environment.
Keep out of direct sun, heat, and too much humidity.
Until you need it, keep it tightly closed in its original container.
You should use reconstituted solutions right away or preserve them according to clinical guidelines.
Why Choose Us
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GMP and Regulatory Compliance: Manufactured according to WHO-GMP, EU- complies with global regulatory standards including WHO-GMP, EU-GMP, and USFDA requirements.
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High Quality & Purity: Strict quality control procedures make sure that each batch is always pure, strong, and stable.
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Regulatory Documentation: We can help you with your Drug Master File (DMF), Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), Stability Data, and Technical Packages.
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International footprints: Trustworthy logistics is always a help in setting footprints globally. We have expertise in delivering orders in both regulated and semi-regulated markets.
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A Trusted Partner: We have years of experience and knowledge administering high-potency oncology APIs while following safety and containment requirements.
